Sandbox Reserved 1136

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[[Image:Susy_reaction.jpg]]
[[Image:Susy_reaction.jpg]]
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It has a fundamental role in the Sucrose flow regulation since it is able to produce Sucrose (used for transportation and stockage) and both ADP-Glucose and UDP-Glucose. It is one of the only four proteins able to synthesize or cleave the Sucrose, thereby Sucrose synthase is implied in many pathways including cell wall, starch and glycoprotein synthesis <ref>Baroja-Fernández, E., Muñoz, F.J., Saikusa, T., Rodríguez-López, M., Akazawa, T. and Pozueta-Romero, J. Sucrose synthase catalyzes the de novo production of ADPglucose linked to starch biosynthesis in heterotrophic tissues of plants. Plant Cell Physiol.</ref>.
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It has a fundamental role in the Sucrose flow regulation since it is able to produce Sucrose (used for transportation and stockage) and both ADP-Glucose and UDP-Glucose. It is one of the only four proteins able to synthesize or cleave the Sucrose, and the only one able to catalyze it in both direction <ref>Salerno GL, Curatti L
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Origin of sucrose metabolism in higher plants: when, how and why?
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Trends Plant Sci. 2003 Feb
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</ref>, thereby Sucrose synthase is implied in many pathways including cell wall, starch and glycoprotein synthesis <ref>Baroja-Fernández, E., Muñoz, F.J., Saikusa, T., Rodríguez-López, M., Akazawa, T. and Pozueta-Romero, J. Sucrose synthase catalyzes the de novo production of ADPglucose linked to starch biosynthesis in heterotrophic tissues of plants. Plant Cell Physiol.</ref>.
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Sucrose synthase catalyses the cleavage reaction at pH around 7 and the synthesis reaction at pH above 9. Therefore, it is a linker between all the pathways that use or synthesize sucrose. SUS is involved in biomass production, nitrogen fixation, fruit and seed maturation and can response to stress (cold, anaerobic conditions, drought or gene induction).
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Revision as of 11:52, 29 January 2016

This Sandbox is Reserved from 15/12/2015, through 15/06/2016 for use in the course "Structural Biology" taught by Bruno Kieffer at the University of Strasbourg, ESBS. This reservation includes Sandbox Reserved 1120 through Sandbox Reserved 1159.
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Structure and Functional aspects of Sucrose Synthase from Arabidopsis thaliana

X-ray crystal structures of AtSus1, as a complex with UDP-glucose at 2.8-Å resolution and as a complex with UDP and fructose at 2.85-Å resolution

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References

• UniProt entry: P49040

• Brenda entry : 2.4.1.13

  1. Salerno GL, Curatti L Origin of sucrose metabolism in higher plants: when, how and why? Trends Plant Sci. 2003 Feb
  2. Baroja-Fernández, E., Muñoz, F.J., Saikusa, T., Rodríguez-López, M., Akazawa, T. and Pozueta-Romero, J. Sucrose synthase catalyzes the de novo production of ADPglucose linked to starch biosynthesis in heterotrophic tissues of plants. Plant Cell Physiol.
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