Chitinase-3-like protein

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<StructureSection load='1hjv' size='350' side='right' scene='45/459222/Cv/1' caption='Chitinase-3-like protein 1 tetramer complex with chitin tetramer and sulfate, [[1hjv]]'>
<StructureSection load='1hjv' size='350' side='right' scene='45/459222/Cv/1' caption='Chitinase-3-like protein 1 tetramer complex with chitin tetramer and sulfate, [[1hjv]]'>
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'''Chitinase-3-like protein 1''' (YKL-40) has a role as an autoantigen in rheumatoid arthritis.The goat, sheep, bovine signaling protein is termed SPG-40, SPS-40 and SPC-40, respectively. For details see [[Molecular Playground/YKL-40]].
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'''Chitinase-3-like protein 1''' (YKL-40) has a role as an autoantigen in rheumatoid arthritis. See also [[Diabetes & Hypoglycemia]] The goat, sheep, bovine signaling protein is termed SPG-40, SPS-40 and SPC-40, respectively. For details see [[Molecular Playground/YKL-40]].
<scene name='45/459222/Cv/2'>Chitin tetramer binding site</scene> (water molecules are shown as red spheres; [[1hjv]]).<ref>PMID:12775711</ref>
<scene name='45/459222/Cv/2'>Chitin tetramer binding site</scene> (water molecules are shown as red spheres; [[1hjv]]).<ref>PMID:12775711</ref>

Revision as of 11:55, 1 February 2016

Chitinase-3-like protein 1 tetramer complex with chitin tetramer and sulfate, 1hjv

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3D Structures of chitinase-3-like protein 1

Updated on 01-February-2016

References

  1. Houston DR, Recklies AD, Krupa JC, van Aalten DM. Structure and ligand-induced conformational change of the 39-kDa glycoprotein from human articular chondrocytes. J Biol Chem. 2003 Aug 8;278(32):30206-12. Epub 2003 May 29. PMID:12775711 doi:10.1074/jbc.M303371200

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