Glucose 6-phosphate dehydrogenase
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | <StructureSection load='1e77' size='350' side='right' caption='Structure of | + | <StructureSection load='1e77' size='350' side='right' caption='Structure of glucose 6-phosphate dehydrogenase complex with glucose 6-phosphate anc Ca+2 ion (green) (PDB code [[1e77]]).' scene=''> |
== Function == | == Function == | ||
| Line 8: | Line 8: | ||
G6PD deficiency predisposes toward hemolytic anemia<ref>PMID:18177777</ref>. | G6PD deficiency predisposes toward hemolytic anemia<ref>PMID:18177777</ref>. | ||
| - | |||
| - | == Relevance == | ||
== Structural highlights == | == Structural highlights == | ||
| + | |||
| + | G6PD active site<ref>PMID:11106478</ref>. | ||
</StructureSection> | </StructureSection> | ||
Revision as of 08:10, 3 February 2016
| |||||||||||
3D structures of glucose 6-phosphate dehydrogenase
Updated on 03-February-2016
References
- ↑ Tian WN, Braunstein LD, Pang J, Stuhlmeier KM, Xi QC, Tian X, Stanton RC. Importance of glucose-6-phosphate dehydrogenase activity for cell growth. J Biol Chem. 1998 Apr 24;273(17):10609-17. PMID:9553122
- ↑ Cappellini MD, Fiorelli G. Glucose-6-phosphate dehydrogenase deficiency. Lancet. 2008 Jan 5;371(9606):64-74. doi: 10.1016/S0140-6736(08)60073-2. PMID:18177777 doi:http://dx.doi.org/10.1016/S0140-6736(08)60073-2
- ↑ Cosgrove MS, Gover S, Naylor CE, Vandeputte-Rutten L, Adams MJ, Levy HR. An examination of the role of asp-177 in the His-Asp catalytic dyad of Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase: X-ray structure and pH dependence of kinetic parameters of the D177N mutant enzyme. Biochemistry. 2000 Dec 12;39(49):15002-11. PMID:11106478
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Joel L. Sussman, Alexander Berchansky, Jaime Prilusky
