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5c0u

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'''Unreleased structure'''
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==Crystal structure of the copper-bound form of MerB mutant D99S==
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<StructureSection load='5c0u' size='340' side='right' caption='[[5c0u]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
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The entry 5c0u is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5c0u]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C0U FirstGlance]. <br>
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Authors: Wahba, H.M., Lecoq, L., Stevenson, M., Mansour, A., Cappadocia, L., Lafrance-Vanasse, J., Wilkinson, K.J., Sygusch, J., Wilcox, D.E., Omichinski, J.G.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3f0p|3f0p]], [[5c0t|5c0t]], [[5c17|5c17]], [[5dsf|5dsf]]</td></tr>
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Description: Crystal structure of the copper-bound form of MerB mutant D99S
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alkylmercury_lyase Alkylmercury lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.2 4.99.1.2] </span></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c0u OCA], [http://pdbe.org/5c0u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c0u RCSB], [http://www.ebi.ac.uk/pdbsum/5c0u PDBsum]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MERB_ECOLX MERB_ECOLX]] Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase (By similarity).
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__TOC__
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</StructureSection>
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[[Category: Alkylmercury lyase]]
[[Category: Cappadocia, L]]
[[Category: Cappadocia, L]]
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[[Category: Wahba, H.M]]
 
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[[Category: Wilkinson, K.J]]
 
[[Category: Lafrance-Vanasse, J]]
[[Category: Lafrance-Vanasse, J]]
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[[Category: Wilcox, D.E]]
 
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[[Category: Stevenson, M]]
 
[[Category: Lecoq, L]]
[[Category: Lecoq, L]]
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[[Category: Omichinski, J.G]]
 
[[Category: Mansour, A]]
[[Category: Mansour, A]]
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[[Category: Omichinski, J G]]
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[[Category: Stevenson, M]]
[[Category: Sygusch, J]]
[[Category: Sygusch, J]]
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[[Category: Wahba, H M]]
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[[Category: Wilcox, D E]]
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[[Category: Wilkinson, K J]]
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[[Category: Bacterial protein]]
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[[Category: Copper]]
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[[Category: Cysteine]]
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[[Category: Escherichia coli]]
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[[Category: Lyase]]
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[[Category: Metal binding protein]]
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[[Category: Mutation]]

Revision as of 15:52, 3 February 2016

Crystal structure of the copper-bound form of MerB mutant D99S

5c0u, resolution 1.87Å

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