5fg6
From Proteopedia
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| - | ''' | + | ==Crystal structure of the bromodomain of human BRD1 (BRPF2) in complex with OF-1 chemical probe== |
| - | + | <StructureSection load='5fg6' size='340' side='right' caption='[[5fg6]], [[Resolution|resolution]] 1.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5fg6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FG6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FG6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5XE:4-BROMANYL-~{N}-(6-METHOXY-1,3-DIMETHYL-2-OXIDANYLIDENE-BENZIMIDAZOL-5-YL)-2-METHYL-BENZENESULFONAMIDE'>5XE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fg6 OCA], [http://pdbe.org/5fg6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fg6 RCSB], [http://www.ebi.ac.uk/pdbsum/5fg6 PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/BRD1_HUMAN BRD1_HUMAN]] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.<ref>PMID:16387653</ref> <ref>PMID:21880731</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arrowsmith, C H]] | ||
| + | [[Category: Bountra, C]] | ||
[[Category: Chaikuad, A]] | [[Category: Chaikuad, A]] | ||
| - | [[Category: | + | [[Category: Delft, F von]] |
| - | [[Category: | + | [[Category: Edwards, A M]] |
[[Category: Fedorov, O]] | [[Category: Fedorov, O]] | ||
| - | [[Category: Muller, S]] | ||
| - | [[Category: Knapp, S]] | ||
| - | [[Category: Bountra, C]] | ||
| - | [[Category: Arrowsmith, C.H]] | ||
| - | [[Category: Von Delft, F]] | ||
[[Category: Filippakopoulos, P]] | [[Category: Filippakopoulos, P]] | ||
| - | [[Category: | + | [[Category: Gerstenberger, B S]] |
| - | [[Category: | + | [[Category: Knapp, S]] |
| + | [[Category: Muller, S]] | ||
| + | [[Category: Nunez-Alonso, G]] | ||
| + | [[Category: Owen, D R]] | ||
[[Category: Savitsky, P]] | [[Category: Savitsky, P]] | ||
| + | [[Category: Tallant, C]] | ||
| + | [[Category: Moz-morf complex]] | ||
| + | [[Category: Transcription]] | ||
Revision as of 15:57, 3 February 2016
Crystal structure of the bromodomain of human BRD1 (BRPF2) in complex with OF-1 chemical probe
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