2wxl
From Proteopedia
(Difference between revisions)
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<StructureSection load='2wxl' size='340' side='right' caption='[[2wxl]], [[Resolution|resolution]] 1.99Å' scene=''> | <StructureSection load='2wxl' size='340' side='right' caption='[[2wxl]], [[Resolution|resolution]] 1.99Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2wxl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2wxl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WXL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WXL FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZS4:2-(DIFLUOROMETHYL)-1-(4,6-DIMORPHOLIN-4-YL-1,3,5-TRIAZIN-2-YL)-1H-BENZIMIDAZOLE'>ZS4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZS4:2-(DIFLUOROMETHYL)-1-(4,6-DIMORPHOLIN-4-YL-1,3,5-TRIAZIN-2-YL)-1H-BENZIMIDAZOLE'>ZS4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wxm|2wxm]], [[2wxh|2wxh]], [[2wxk|2wxk]], [[2wxg|2wxg]], [[2wxi|2wxi]], [[2wxp|2wxp]], [[2wxo|2wxo]], [[2wxf|2wxf]], [[2wxq|2wxq]], [[2wxn|2wxn]], [[2wxe|2wxe]], [[2wxj|2wxj]], [[2wxr|2wxr]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wxm|2wxm]], [[2wxh|2wxh]], [[2wxk|2wxk]], [[2wxg|2wxg]], [[2wxi|2wxi]], [[2wxp|2wxp]], [[2wxo|2wxo]], [[2wxf|2wxf]], [[2wxq|2wxq]], [[2wxn|2wxn]], [[2wxe|2wxe]], [[2wxj|2wxj]], [[2wxr|2wxr]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphatidylinositol-4,5-bisphosphate_3-kinase Phosphatidylinositol-4,5-bisphosphate 3-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.153 2.7.1.153] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphatidylinositol-4,5-bisphosphate_3-kinase Phosphatidylinositol-4,5-bisphosphate 3-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.153 2.7.1.153] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wxl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wxl RCSB], [http://www.ebi.ac.uk/pdbsum/2wxl PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wxl OCA], [http://pdbe.org/2wxl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wxl RCSB], [http://www.ebi.ac.uk/pdbsum/2wxl PDBsum]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wxl ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2wxl" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Lk3 transgenic mice]] |
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]] | [[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]] | ||
[[Category: Berndt, A]] | [[Category: Berndt, A]] | ||
Revision as of 07:30, 7 February 2016
THE CRYSTAL STRUCTURE OF THE MURINE CLASS IA PI 3-KINASE P110DELTA IN COMPLEX WITH ZSTK474.
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Categories: Lk3 transgenic mice | Phosphatidylinositol-4,5-bisphosphate 3-kinase | Berndt, A | Gaillard, P | Gorrec, F | Hon, W C | Houseman, B T | Lee, D D | Liu, Y | Miller, S | Pacold, J I | Rommel, C | Ruckle, T | Schwarz, M K | Shaw, J P | Shokat, K M | Williams, O | Williams, R L | Cancer | Isoform-specific inhibitor | Phosphoprotein | Transferase
