3inq
From Proteopedia
(Difference between revisions)
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<StructureSection load='3inq' size='340' side='right' caption='[[3inq]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='3inq' size='340' side='right' caption='[[3inq]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3inq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3inq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3INQ FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=X0J:4-[4-(BIPHENYL-3-YLMETHYL)PIPERAZIN-1-YL]-N-{[4-({(1R)-3-(DIMETHYLAMINO)-1-[(PHENYLSULFANYL)METHYL]PROPYL}AMINO)-3-NITROPHENYL]SULFONYL}BENZAMIDE'>X0J</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=X0J:4-[4-(BIPHENYL-3-YLMETHYL)PIPERAZIN-1-YL]-N-{[4-({(1R)-3-(DIMETHYLAMINO)-1-[(PHENYLSULFANYL)METHYL]PROPYL}AMINO)-3-NITROPHENYL]SULFONYL}BENZAMIDE'>X0J</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yxj|2yxj]], [[3fdl|3fdl]], [[2p1l|2p1l]], [[3io8|3io8]], [[3io9|3io9]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yxj|2yxj]], [[3fdl|3fdl]], [[2p1l|2p1l]], [[3io8|3io8]], [[3io9|3io9]]</td></tr> | ||
- | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BCL-X ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BCL-X ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3inq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3inq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3inq RCSB], [http://www.ebi.ac.uk/pdbsum/3inq PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3inq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3inq OCA], [http://pdbe.org/3inq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3inq RCSB], [http://www.ebi.ac.uk/pdbsum/3inq PDBsum]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
- | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3inq ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Human]] |
[[Category: Colman, P M]] | [[Category: Colman, P M]] | ||
[[Category: Czabotar, P E]] | [[Category: Czabotar, P E]] |
Revision as of 08:55, 7 February 2016
Crystal structure of BCL-XL in complex with W1191542
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Categories: Human | Colman, P M | Czabotar, P E | Fairlie, W D | Lee, E F | Smith, B J | Apoptosis | Membrane | Mitochondrion | Nucleus | Transmembrane