1csn
From Proteopedia
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|PDB= 1csn |SIZE=350|CAPTION= <scene name='initialview01'>1csn</scene>, resolution 2.0Å | |PDB= 1csn |SIZE=350|CAPTION= <scene name='initialview01'>1csn</scene>, resolution 2.0Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=ATP:ADENOSINE-5'-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1csn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1csn OCA], [http://www.ebi.ac.uk/pdbsum/1csn PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1csn RCSB]</span> | ||
}} | }} | ||
| Line 24: | Line 27: | ||
[[Category: Cheng, X.]] | [[Category: Cheng, X.]] | ||
[[Category: Xu, R M.]] | [[Category: Xu, R M.]] | ||
| - | [[Category: ATP]] | ||
| - | [[Category: MG]] | ||
| - | [[Category: SO4]] | ||
[[Category: phosphotransferase]] | [[Category: phosphotransferase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:27:48 2008'' |
Revision as of 16:27, 30 March 2008
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| , resolution 2.0Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
BINARY COMPLEX OF CASEIN KINASE-1 WITH MGATP
Overview
The structure of a truncated variant of casein kinase-1 from Schizosaccharomyces pombe, has been determined in complex with MgATP at 2.0 A resolution. The model resembles the 'closed', ATP-bound conformations of the cyclin-dependent kinase 2 and the cAMP-dependent protein kinase, with clear differences in the structure of surface loops that impart unique features to casein kinase-1. The structure is of unphosphorylated, active conformation of casein kinase-1 and the peptide-binding site is fully accessible to substrate.
About this Structure
1CSN is a Single protein structure of sequence from Schizosaccharomyces pombe. Full crystallographic information is available from OCA.
Reference
Crystal structure of casein kinase-1, a phosphate-directed protein kinase., Xu RM, Carmel G, Sweet RM, Kuret J, Cheng X, EMBO J. 1995 Mar 1;14(5):1015-23. PMID:7889932
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