2e7b
From Proteopedia
(Difference between revisions)
| Line 2: | Line 2: | ||
<StructureSection load='2e7b' size='340' side='right' caption='[[2e7b]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2e7b' size='340' side='right' caption='[[2e7b]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2e7b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2e7b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E7B FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">OBSCN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">OBSCN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e7b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e7b RCSB], [http://www.ebi.ac.uk/pdbsum/2e7b PDBsum], [http://www.topsan.org/Proteins/RSGI/2e7b TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e7b OCA], [http://pdbe.org/2e7b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2e7b RCSB], [http://www.ebi.ac.uk/pdbsum/2e7b PDBsum], [http://www.topsan.org/Proteins/RSGI/2e7b TOPSAN]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/OBSCN_HUMAN OBSCN_HUMAN]] Involved in myofibrillogenesis. Seems to be involved in assembly of myosin into sarcomeric A bands in striated muscle. Isoform 3 together with ANK1 isoform Mu17/Ank1.5 may provide a molecular link between the sarcoplasmic reticulum and myofibrils.<ref>PMID:11448995</ref> <ref>PMID:16205939</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 14: | Line 16: | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e7b ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| Line 20: | Line 22: | ||
*[[Group:MUZIC:Obscurin|MUZIC:Obscurin]] | *[[Group:MUZIC:Obscurin|MUZIC:Obscurin]] | ||
*[[Obscurin|Obscurin]] | *[[Obscurin|Obscurin]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Hayashi, F]] | [[Category: Hayashi, F]] | ||
[[Category: Nagashima, T]] | [[Category: Nagashima, T]] | ||
Revision as of 00:22, 8 February 2016
Solution structure of the 6th Ig-like domain from human KIAA1556
| |||||||||||

