1dus
From Proteopedia
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|GENE= | |GENE= | ||
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam05175 MTS]</span> | |DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam05175 MTS]</span> | ||
- | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dus OCA], [http://www.ebi.ac.uk/pdbsum/1dus PDBsum | + | |RELATEDENTRY= |
+ | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dus OCA], [http://www.ebi.ac.uk/pdbsum/1dus PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1dus RCSB]</span> | ||
}} | }} | ||
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[[Category: structural genomic]] | [[Category: structural genomic]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:49:07 2008'' |
Revision as of 16:49, 30 March 2008
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, resolution 1.80Å | |||||||
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Ligands: | |||||||
Domains: | MTS | ||||||
Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
Coordinates: | save as pdb, mmCIF, xml |
MJ0882-A hypothetical protein from M. jannaschii
Overview
We have determined the three-dimensional (3-D) structure of protein MJ0882, which derives from a hypothetical open reading frame in the genome of the hyperthermophile Methanococcus jannaschii. The 3-D fold of MJ0882 at 1.8 A highly resembles that of a methyltransferase, despite limited sequence similarity to any confirmed methyltransferase. The structure has an S-adenosylmethionine (AdoMet) binding pocket surrounded by motifs with similarities to those commonly found among AdoMet binding proteins. Preliminary biochemical experiments show that MJ0882 specifically binds to AdoMet, which is the essential co-factor for methyltransferases.
About this Structure
1DUS is a Single protein structure of sequence from Methanocaldococcus jannaschii. Full crystallographic information is available from OCA.
Reference
Structure-based experimental confirmation of biochemical function to a methyltransferase, MJ0882, from hyperthermophile Methanococcus jannaschii., Huang L, Hung L, Odell M, Yokota H, Kim R, Kim SH, J Struct Funct Genomics. 2002;2(3):121-7. PMID:12836702
Page seeded by OCA on Sun Mar 30 19:49:07 2008
Categories: Methanocaldococcus jannaschii | Single protein | BSGC, Berkeley Structural Genomics Center. | Huang, L. | Hung, L. | Kim, R. | Kim, S H. | Berkeley structural genomics center | Bsgc structure funded by nih | Hypothetical protein | Methanococcus jannaschii | Protein structure initiative | Psi | Structural genomic