2vcj
From Proteopedia
(Difference between revisions)
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<StructureSection load='2vcj' size='340' side='right' caption='[[2vcj]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='2vcj' size='340' side='right' caption='[[2vcj]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2vcj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2vcj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VCJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VCJ FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2EQ:5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-[4-(MORPHOLIN-4-YLMETHYL)PHENYL]ISOXAZOLE-3-CARBOXAMIDE'>2EQ</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2EQ:5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-[4-(MORPHOLIN-4-YLMETHYL)PHENYL]ISOXAZOLE-3-CARBOXAMIDE'>2EQ</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cdd|2cdd]], [[1uy9|1uy9]], [[1uy6|1uy6]], [[1byq|1byq]], [[2bsm|2bsm]], [[1osf|1osf]], [[1yc4|1yc4]], [[1uy8|1uy8]], [[2bug|2bug]], [[2uwd|2uwd]], [[2c2l|2c2l]], [[1uyk|1uyk]], [[1uyh|1uyh]], [[2cct|2cct]], [[2bt0|2bt0]], [[1uyg|1uyg]], [[1uye|1uye]], [[1uyl|1uyl]], [[2ccu|2ccu]], [[2bz5|2bz5]], [[1yc1|1yc1]], [[2ccs|2ccs]], [[1uyc|1uyc]], [[1uy7|1uy7]], [[1yc3|1yc3]], [[1uyf|1uyf]], [[1uyi|1uyi]], [[2byh|2byh]], [[1uyd|1uyd]], [[2byi|2byi]], [[2vci|2vci]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cdd|2cdd]], [[1uy9|1uy9]], [[1uy6|1uy6]], [[1byq|1byq]], [[2bsm|2bsm]], [[1osf|1osf]], [[1yc4|1yc4]], [[1uy8|1uy8]], [[2bug|2bug]], [[2uwd|2uwd]], [[2c2l|2c2l]], [[1uyk|1uyk]], [[1uyh|1uyh]], [[2cct|2cct]], [[2bt0|2bt0]], [[1uyg|1uyg]], [[1uye|1uye]], [[1uyl|1uyl]], [[2ccu|2ccu]], [[2bz5|2bz5]], [[1yc1|1yc1]], [[2ccs|2ccs]], [[1uyc|1uyc]], [[1uy7|1uy7]], [[1yc3|1yc3]], [[1uyf|1uyf]], [[1uyi|1uyi]], [[2byh|2byh]], [[1uyd|1uyd]], [[2byi|2byi]], [[2vci|2vci]]</td></tr> | ||
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vcj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vcj RCSB], [http://www.ebi.ac.uk/pdbsum/2vcj PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vcj OCA], [http://pdbe.org/2vcj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vcj RCSB], [http://www.ebi.ac.uk/pdbsum/2vcj PDBsum]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
- | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vcj ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
+ | <div class="pdbe-citations 2vcj" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Human]] |
[[Category: Aherne, W]] | [[Category: Aherne, W]] | ||
[[Category: Barril, X]] | [[Category: Barril, X]] |
Revision as of 16:36, 8 February 2016
4,5 DIARYL ISOXAZOLE HSP90 CHAPERONE INHIBITORS: POTENTIAL THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER
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Categories: Human | Aherne, W | Barril, X | Borgognoni, J | Boxal, K | Brough, P A | Cansfield, J E | Cheung, K M | Collins, I | Davies, N G.M | Drysdale, M J | Dymock, B | Eccles, S A | Finch, H | Fink, A | Hayes, A | Howes, R | Hubbard, R E | James, K | Jordan, A M | Lockie, A | Martins, V | Massey, A | Matthews, T P | Mcdonald, E | Northfield, C J | Pearl, L H | Prodromou, C | Ray, S | Raynaud, F I | Roughley, S D | Sharp, S Y | Surgenor, A | Walmsley, D L | Webb, P | Wood, M | Workman, P | Wright, L | Atp-binding | Chaperone | Nucleotide-binding | Phosphorylation | Stress response