We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
Ephrin
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | <StructureSection load='3mx0' size='340' side='right' caption='Structure of glycosylated human ephrin-A5 receptor-binding domain | + | <StructureSection load='3mx0' size='340' side='right' caption='Structure of glycosylated human ephrin-A5 receptor-binding domain complex with ephrin type A receptor 2 (PDB code [[3mx0]]).' scene='59/594659/Cv/1'> |
== Function == | == Function == | ||
| Line 7: | Line 7: | ||
== Disease == | == Disease == | ||
Eph-A5 is implicated in spinal cord injury. Eph-A1 is implicated in myocardial injury and renal reperfusion injury. | Eph-A5 is implicated in spinal cord injury. Eph-A1 is implicated in myocardial injury and renal reperfusion injury. | ||
| + | |||
| + | == Structural highlights == | ||
| + | |||
| + | <scene name='59/594659/Cv/2'>Ephrin-A5 receptor-binding domain complex with ephrin type A receptor 2</scene> (PDB code [[3mx0]]).<ref>PMID:20505120</ref> | ||
</StructureSection> | </StructureSection> | ||
Revision as of 13:26, 9 February 2016
| |||||||||||
3D structures of ephrin
Updated on 09-February-2016
References
- ↑ Egea J, Klein R. Bidirectional Eph-ephrin signaling during axon guidance. Trends Cell Biol. 2007 May;17(5):230-8. Epub 2007 Apr 8. PMID:17420126 doi:http://dx.doi.org/10.1016/j.tcb.2007.03.004
- ↑ Himanen JP, Yermekbayeva L, Janes PW, Walker JR, Xu K, Atapattu L, Rajashankar KR, Mensinga A, Lackmann M, Nikolov DB, Dhe-Paganon S. Architecture of Eph receptor clusters. Proc Natl Acad Sci U S A. 2010 May 26. PMID:20505120
