1mem

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==About this Structure==
==About this Structure==
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1MEM is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]] with BZP and BNS as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Cathepsin_K Cathepsin K]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.38 3.4.22.38]]. Structure known Active Site: CAT. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1MEM OCA]].
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1MEM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with BZP and BNS as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Cathepsin_K Cathepsin K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.38 3.4.22.38] Structure known Active Site: CAT. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1MEM OCA].
==Reference==
==Reference==
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[[Category: protease]]
[[Category: protease]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 15:42:54 2007''
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 5 15:22:31 2007''

Revision as of 13:17, 5 November 2007


1mem, resolution 1.8Å

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CRYSTAL STRUCTURE OF CATHEPSIN K COMPLEXED WITH A POTENT VINYL SULFONE INHIBITOR

About this Structure

1MEM is a Single protein structure of sequence from Homo sapiens with BZP and BNS as ligands. Active as Cathepsin K, with EC number 3.4.22.38 Structure known Active Site: CAT. Full crystallographic information is available from OCA.

Reference

Crystal structure of human cathepsin K complexed with a potent inhibitor., McGrath ME, Klaus JL, Barnes MG, Bromme D, Nat Struct Biol. 1997 Feb;4(2):105-9. PMID:9033587

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