This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1f62
From Proteopedia
| Line 4: | Line 4: | ||
|PDB= 1f62 |SIZE=350|CAPTION= <scene name='initialview01'>1f62</scene> | |PDB= 1f62 |SIZE=350|CAPTION= <scene name='initialview01'>1f62</scene> | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=ZN:ZINC ION'>ZN</scene> | + | |LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1f62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f62 OCA], [http://www.ebi.ac.uk/pdbsum/1f62 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1f62 RCSB]</span> | ||
}} | }} | ||
| Line 26: | Line 29: | ||
[[Category: Pascual, J.]] | [[Category: Pascual, J.]] | ||
[[Category: Wright, P E.]] | [[Category: Wright, P E.]] | ||
| - | [[Category: ZN]] | ||
[[Category: zn-finger]] | [[Category: zn-finger]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:16:41 2008'' |
Revision as of 17:16, 30 March 2008
| |||||||
| Ligands: | |||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
WSTF-PHD
Overview
The PHD (plant homeo domain) is a approximately 50-residue motif found mainly in proteins involved in eukaryotic transcription regulation. The characteristic sequence feature is a conserved Cys(4)-HisCys(3) zinc binding motif. We have determined the solution structure of the PHD motif from the human Williams-Beuren syndrome transcription factor (WSTF) protein. The domain folds into an interleaved zinc finger which binds two Zn(2+) in a similar manner to that of the RING and FYVE domains. The structure reveals a conserved zinc-binding core, together with two variable loops that are likely candidates for interactions between the various PHD domains and their specific ligands.
About this Structure
1F62 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Structure of the PHD zinc finger from human Williams-Beuren syndrome transcription factor., Pascual J, Martinez-Yamout M, Dyson HJ, Wright PE, J Mol Biol. 2000 Dec 15;304(5):723-9. PMID:11124022
Page seeded by OCA on Sun Mar 30 20:16:41 2008
