1ftn
From Proteopedia
(Difference between revisions)
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|PDB= 1ftn |SIZE=350|CAPTION= <scene name='initialview01'>1ftn</scene>, resolution 2.1Å | |PDB= 1ftn |SIZE=350|CAPTION= <scene name='initialview01'>1ftn</scene>, resolution 2.1Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=GDP:GUANOSINE-5'-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= SYNTHETIC HUMAN RHOA GENE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= SYNTHETIC HUMAN RHOA GENE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ftn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ftn OCA], [http://www.ebi.ac.uk/pdbsum/1ftn PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ftn RCSB]</span> | ||
}} | }} | ||
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[[Category: Wei, Y.]] | [[Category: Wei, Y.]] | ||
[[Category: Zhang, Y.]] | [[Category: Zhang, Y.]] | ||
| - | [[Category: GDP]] | ||
| - | [[Category: MG]] | ||
[[Category: gtp-binding]] | [[Category: gtp-binding]] | ||
[[Category: lipoprotein]] | [[Category: lipoprotein]] | ||
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[[Category: small p-protein]] | [[Category: small p-protein]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:30:08 2008'' |
Revision as of 17:30, 30 March 2008
| |||||||
| , resolution 2.1Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Gene: | SYNTHETIC HUMAN RHOA GENE (Homo sapiens) | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX
Overview
RhoA, a ubiquitous intracellular GTPase, mediates cytoskeletal responses to extracellular signals. A 2.1 A resolution crystal structure of the human RhoA-GDP complex shows unique stereochemistry in the switch I region, which results in a novel mode of Mg2+ binding.
About this Structure
1FTN is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Crystal structure of RhoA-GDP and its functional implications., Wei Y, Zhang Y, Derewenda U, Liu X, Minor W, Nakamoto RK, Somlyo AV, Somlyo AP, Derewenda ZS, Nat Struct Biol. 1997 Sep;4(9):699-703. PMID:9302995
Page seeded by OCA on Sun Mar 30 20:30:08 2008
