Bromodomain-containing protein
From Proteopedia
(Difference between revisions)
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| - | <StructureSection load='3p5o' size=' | + | <StructureSection load='3p5o' size='350' side='right' caption='Human bromodomain-containing protein 4 bromodomain 1 complex with inhibitor and ethylene glycol (PDB code [[3p5o]])' scene='72/724778/Cv/1'> |
== Function == | == Function == | ||
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== Structural highlights == | == Structural highlights == | ||
| - | BRD4 bromodomain 1 inhibitors bind to the acetyl-binding pocket<ref>PMID:18552174</ref>. | + | <scene name='72/724778/Cv/3'>BRD4 bromodomain 1 inhibitors bind to the acetyl-binding pocket</scene><ref>PMID:18552174</ref>. |
</StructureSection> | </StructureSection> | ||
Revision as of 11:16, 10 February 2016
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3D Structures of bromodomain-containing protein
Updated on 10-February-2016
References
- ↑ Zeng L, Zhou MM. Bromodomain: an acetyl-lysine binding domain. FEBS Lett. 2002 Feb 20;513(1):124-8. PMID:11911891
- ↑ Belkina AC, Denis GV. BET domain co-regulators in obesity, inflammation and cancer. Nat Rev Cancer. 2012 Jun 22;12(7):465-77. doi: 10.1038/nrc3256. PMID:22722403 doi:http://dx.doi.org/10.1038/nrc3256
- ↑ French CA. Demystified molecular pathology of NUT midline carcinomas. J Clin Pathol. 2010 Jun;63(6):492-6. doi: 10.1136/jcp.2007.052902. Epub 2008 Jun , 13. PMID:18552174 doi:http://dx.doi.org/10.1136/jcp.2007.052902
- ↑ French CA. Demystified molecular pathology of NUT midline carcinomas. J Clin Pathol. 2010 Jun;63(6):492-6. doi: 10.1136/jcp.2007.052902. Epub 2008 Jun , 13. PMID:18552174 doi:http://dx.doi.org/10.1136/jcp.2007.052902
