This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Response regulator
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_1kgs| PDB=1kgs | SIZE= | + | {{STRUCTURE_1kgs| PDB=1kgs | SIZE=350| SCENE= |right|CAPTION=Se-Met DNA-binding response regulator D complex with thiocyanate, [[1kgs]] }} |
'''Response regulators''' (RR) are part of the two-component signal transduction systems which enable bacteria to sense and respond to a wide range of environments. | '''Response regulators''' (RR) are part of the two-component signal transduction systems which enable bacteria to sense and respond to a wide range of environments. | ||
Revision as of 11:40, 10 February 2016
Response regulators (RR) are part of the two-component signal transduction systems which enable bacteria to sense and respond to a wide range of environments.
Two-component RR is a complex of histidine kinase (sensor protein SP) and RR. The RR act as phosphorylation-activated switches. Most RR consist of N terminal shich is the signal receiving domain and C terminal which is the DNA-binding domain. RR CheY is a chemotaxis response regulator in bacteria. RR Spo0 is the sporulation response regulator. For details see:
For PleD:
- PleD activation
- PleD allosteric product inhibition
- PleD catalysis
- Response regulator PLED in complex with C-di-GMP
For PhoP:
For photosynthetic apparatus RR:
For WspR RR:
- WspR.
3D Structures of response regulator
Updated on 10-February-2016
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Joel L. Sussman, Alexander Berchansky, Jaime Prilusky
