4wrc
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal Structure of Surfactant Protein-A DEDN Mutant (E171D/P175E/R197N/K203D)== |
| - | + | <StructureSection load='4wrc' size='340' side='right' caption='[[4wrc]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4wrc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WRC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WRC FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HEZ:HEXANE-1,6-DIOL'>HEZ</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wre|4wre]], [[4wrf|4wrf]], [[4wr9|4wr9]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wrc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wrc OCA], [http://pdbe.org/4wrc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wrc RCSB], [http://www.ebi.ac.uk/pdbsum/4wrc PDBsum]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: Head, J | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/SFTPA_RAT SFTPA_RAT]] In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Cafarella, T R]] |
| + | [[Category: Head, J F]] | ||
| + | [[Category: McCormack, F X]] | ||
| + | [[Category: Nikolaidis, N M]] | ||
| + | [[Category: Rynkiewicz, M J]] | ||
| + | [[Category: Seaton, B A]] | ||
[[Category: Wu, H]] | [[Category: Wu, H]] | ||
| - | [[Category: | + | [[Category: Carbohydrate binding]] |
| + | [[Category: Collectin]] | ||
| + | [[Category: Lectin]] | ||
| + | [[Category: Lipid binding]] | ||
| + | [[Category: Sugar binding protein]] | ||
Revision as of 17:20, 10 February 2016
Crystal Structure of Surfactant Protein-A DEDN Mutant (E171D/P175E/R197N/K203D)
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