This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4wuw
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ''' | + | ==Crystal Structure of Surfactant Protein-A DED Mutant (E171D/P175E/K203D) Complexed with Inositol== |
| - | + | <StructureSection load='4wuw' size='340' side='right' caption='[[4wuw]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4wuw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WUW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WUW FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=INS:1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE'>INS</scene></td></tr> | |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MHO:S-OXYMETHIONINE'>MHO</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wux|4wux]]</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wuw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wuw OCA], [http://pdbe.org/4wuw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wuw RCSB], [http://www.ebi.ac.uk/pdbsum/4wuw PDBsum]</span></td></tr> |
| - | [[Category: Head, J | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/SFTPA_RAT SFTPA_RAT]] In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Cafarella, T R]] | ||
| + | [[Category: Head, J F]] | ||
| + | [[Category: McCormack, F X]] | ||
| + | [[Category: Nikolaidis, N M]] | ||
| + | [[Category: Rynkiewicz, M J]] | ||
| + | [[Category: Seaton, B A]] | ||
[[Category: Wu, H]] | [[Category: Wu, H]] | ||
| - | [[Category: | + | [[Category: Carbohydrate binding]] |
| + | [[Category: Collectin]] | ||
| + | [[Category: Lectin]] | ||
| + | [[Category: Lipid binding]] | ||
| + | [[Category: Sugar binding protein]] | ||
Revision as of 17:20, 10 February 2016
Crystal Structure of Surfactant Protein-A DED Mutant (E171D/P175E/K203D) Complexed with Inositol
| |||||||||||
