4wux

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'''Unreleased structure'''
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==Crystal Structure of Surfactant Protein-A DED Mutant (E171D/P175E/K203D) Complexed with Mannose==
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<StructureSection load='4wux' size='340' side='right' caption='[[4wux]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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The entry 4wux is ON HOLD until Feb 10 2017
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4wux]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WUX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WUX FirstGlance]. <br>
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Authors: Rynkiewicz, M.J., Wu, H., Cafarella, T.R., Nikolaidis, N.M., Head, J.F., Seaton, B.A., McCormack, F.X.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MHO:S-OXYMETHIONINE'>MHO</scene></td></tr>
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Description: Crystal Structure of Surfactant Protein-A DED Mutant (E171D/P175E/K203D) Complexed with Mannose
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wuw|4wuw]]</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wux FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wux OCA], [http://pdbe.org/4wux PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wux RCSB], [http://www.ebi.ac.uk/pdbsum/4wux PDBsum]</span></td></tr>
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[[Category: Head, J.F]]
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</table>
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[[Category: Seaton, B.A]]
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== Function ==
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[[Category: Mccormack, F.X]]
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[[http://www.uniprot.org/uniprot/SFTPA_RAT SFTPA_RAT]] In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.
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[[Category: Cafarella, T.R]]
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__TOC__
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[[Category: Nikolaidis, N.M]]
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</StructureSection>
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[[Category: Cafarella, T R]]
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[[Category: Head, J F]]
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[[Category: McCormack, F X]]
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[[Category: Nikolaidis, N M]]
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[[Category: Rynkiewicz, M J]]
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[[Category: Seaton, B A]]
[[Category: Wu, H]]
[[Category: Wu, H]]
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[[Category: Rynkiewicz, M.J]]
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[[Category: Carbohydrate binding]]
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[[Category: Collectin]]
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[[Category: Lectin]]
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[[Category: Lipid binding]]
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[[Category: Sugar binding protein]]

Revision as of 17:21, 10 February 2016

Crystal Structure of Surfactant Protein-A DED Mutant (E171D/P175E/K203D) Complexed with Mannose

4wux, resolution 1.90Å

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