Exonuclease

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* '''ExN-V''' cleaves linear double-stranded DNA.<br />
* '''ExN-V''' cleaves linear double-stranded DNA.<br />
* '''ExN-VIII''' requires a free 5’ OH group for reacting.<br />
* '''ExN-VIII''' requires a free 5’ OH group for reacting.<br />
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<scene name='46/466467/Cv/2'>Mg coordination site</scene> in ''E. coli'' exonuclease (PDB code [[1fxx]]).<ref>PMID:11101894</ref>
</StructureSection>
</StructureSection>

Revision as of 13:06, 14 February 2016

E. coli exonuclease I complex with phosphate, glycerol and Mg+2 ion (PDB code 1fxx)

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3D Structures of exonuclease

Updated on 14-February-2016

References

  1. ↑ Mukherjee D, Fritz DT, Kilpatrick WJ, Gao M, Wilusz J. Analysis of RNA exonucleolytic activities in cellular extracts. Methods Mol Biol. 2004;257:193-212. PMID:14770007 doi:http://dx.doi.org/10.1385/1-59259-750-5:193
  2. ↑ Breyer WA, Matthews BW. Structure of Escherichia coli exonuclease I suggests how processivity is achieved. Nat Struct Biol. 2000 Dec;7(12):1125-8. PMID:11101894 doi:10.1038/81978

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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