Factor inhibiting HIF

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For details on '''Factor inhibiting HIF''' see [[Molecular Playground/FIH]]. HIF is hypoxia-inducible factor - transcription factors that respond to hypoxia, i.e., decrease in oxygen<ref>PMID:23606740</ref>. <scene name='48/480806/Cv/2'>Dimeric factor inhibiting HIF with oxogluterate derivative</scene>.
For details on '''Factor inhibiting HIF''' see [[Molecular Playground/FIH]]. HIF is hypoxia-inducible factor - transcription factors that respond to hypoxia, i.e., decrease in oxygen<ref>PMID:23606740</ref>. <scene name='48/480806/Cv/2'>Dimeric factor inhibiting HIF with oxogluterate derivative</scene>.
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<scene name='48/480806/Cv/4'>Fe/2-oxogluterate binding site</scene> PDB code [[1mzf]]).<ref>PMID:12432100</ref>
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<scene name='48/480806/Cv/4'>Fe/2-oxogluterate binding site</scene> (PDB code [[1mzf]]).<ref>PMID:12432100</ref>
</StructureSection>
</StructureSection>
== 3D Structures of factor inhibiting HIF ==
== 3D Structures of factor inhibiting HIF ==

Revision as of 12:31, 15 February 2016

Dimeric factor inhibiting HIF complex with oxogluterate derivative (PDB code 1mzf)

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3D Structures of factor inhibiting HIF

Updated on 15-February-2016

References

  1. Janke K, Brockmeier U, Kuhlmann K, Eisenacher M, Nolde J, Meyer HE, Mairbaurl H, Metzen E. Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2). J Cell Sci. 2013 Jun 15;126(Pt 12):2629-40. doi: 10.1242/jcs.117564. Epub 2013, Apr 19. PMID:23606740 doi:http://dx.doi.org/10.1242/jcs.117564
  2. Dann CE 3rd, Bruick RK, Deisenhofer J. Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway. Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15351-6. Epub 2002 Nov 13. PMID:12432100 doi:http://dx.doi.org/10.1073/pnas.202614999

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