Sandbox Reserved 427
From Proteopedia
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==Additional Features== | ==Additional Features== | ||
<Structure load='1j7e' size='300' frame='true' align='right' caption='1j7e, Vitamin D Binding Protein binds to many different different substrates including actin and various synthetic ligands.' scene='Insert optional scene name here' /> | <Structure load='1j7e' size='300' frame='true' align='right' caption='1j7e, Vitamin D Binding Protein binds to many different different substrates including actin and various synthetic ligands.' scene='Insert optional scene name here' /> | ||
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=====Actin Binding Interactions===== | =====Actin Binding Interactions===== | ||
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=====Other Notable Ligands===== | =====Other Notable Ligands===== | ||
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==Quiz Question 1== | ==Quiz Question 1== | ||
Revision as of 00:01, 16 February 2016
| This Sandbox is Reserved from January 19, 2016, through August 31, 2016 for use for Proteopedia Team Projects by the class Chemistry 423 Biochemistry for Chemists taught by Lynmarie K Thompson at University of Massachusetts Amherst, USA. This reservation includes Sandbox Reserved 425 through Sandbox Reserved 439. |
Contents |
Vitamin D binding protein (1j7e)
Student Projects for UMass Chemistry 423 Spring 2016
Introduction
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This is a sample scene created with SAT to by Group, and another to make of the protein.
Overall Structure
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This scene highlights the in pink in the protein and the binding sights in green.
Binding Interactions
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Additional Features
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Actin Binding Interactions
Inhibitors
Role in Disease
Other Notable Ligands
Quiz Question 1
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Vitamin D binding protein can be compared to ...
See Also
Credits
Introduction - Uday Prakhya
Overall Structure - Elizabeth Swanson
Drug Binding Site - Alex Debreceni
Additional Features - Nick Rivelli
Quiz Question 1 - Robert Green
References
[1] Gomme PT, Bertolini J. 2004. Therapeutic potential of vitamin D-binding protein. Trends Biotechnol. 22:340–345.
[2] Haddad JG. 1995. Plasma vitamin D-binding protein (Gc-globulin): Multiple tasks. J. Steroid Biochem. Mol. Biol. 53:579–582.
[3] Otterbein LR, Cosio C, Graceffa P, Dominguez R. 2002. Crystal structures of the vitamin D-binding protein and its complex with actin: structural basis of the actin-scavenger system. Proc. Natl. Acad. Sci. U. S. A. 99:8003–8008.
[4] Speeckaert M, Huang G, Delanghe JR, Taes YEC. 2006. Biological and clinical aspects of the vitamin D binding protein (Gc-globulin) and its polymorphism. Clin. Chim. Acta 372:33–42.
[5] Verboven C, Rabijns A, De Maeyer M, Van Baelen H, Bouillon R, De Ranter C. 2002. A structural basis for the unique binding features of the human vitamin D-binding protein. Nat. Struct. Biol. 9:131–6.
[6] White P, Cooke N. 2000. The multifunctional properties and characteristics of vitamin D-binding protein. Trends Endocrinol. Metab. 11:320–327.
