Epidermal growth factor

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== Function ==
== Function ==
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'''Epidermal growth factor''' (EGF) plays a role in cell growth. It binds to its receptor ([[Epidermal Growth Factor Receptor|EGFR]]). EGF is regulated by iodine. EGF is part of a family of proteins with similar structure and activity.<ref>PMID:2186024</ref> Some details on EGF exon in [[EGF1]]; on Gla domain in [[Gla domain]].
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'''Epidermal growth factor''' (EGF) plays a role in cell growth. It binds to its receptor ([[Epidermal Growth Factor Receptor|EGFR]]). EGF is regulated by iodine. EGF is part of a family of proteins with similar structure and activity.<ref>PMID:2186024</ref> Some details<br />
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on EGF exon in [[EGF1]]<br />
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on Gla domain in [[Gla domain]]<br />
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[[Pre-prozymogen]].
== Relevance ==
== Relevance ==

Revision as of 09:11, 18 February 2016

Dimer of the monomeric human epidermal growth factor (PDB code 1jl9)

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3D structures of epidermal growth factor

Updated on 18-February-2016

References

  1. Carpenter G, Cohen S. Epidermal growth factor. J Biol Chem. 1990 May 15;265(14):7709-12. PMID:2186024
  2. Lu HS, Chai JJ, Li M, Huang BR, He CH, Bi RC. Crystal structure of human epidermal growth factor and its dimerization. J Biol Chem. 2001 Sep 14;276(37):34913-7. Epub 2001 Jul 3. PMID:11438527 doi:10.1074/jbc.M102874200

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Michal Harel, Alexander Berchansky

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