4y0i

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'''Unreleased structure'''
 
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The entry 4y0i is ON HOLD until Paper Publication
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==GABA-aminotransferase inactivated by conformationally-restricted inactivator==
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<StructureSection load='4y0i' size='340' side='right' caption='[[4y0i]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
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Authors: Wu, R., Sanishvili, R., Lee, H.V., Dustin, D.H., Emma, D., Neil, K., Silverman, R.B., Liu, D.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4y0i]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y0I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y0I FirstGlance]. <br>
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Description: GABA-aminotransferase inactivated by conformationally-restricted inactivator
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PSZ:4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC+ACID'>PSZ</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y0i OCA], [http://pdbe.org/4y0i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y0i RCSB], [http://www.ebi.ac.uk/pdbsum/4y0i PDBsum]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/GABT_PIG GABT_PIG]] Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.
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__TOC__
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</StructureSection>
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[[Category: Dustin, D H]]
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[[Category: Emma, D]]
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[[Category: Lee, H V]]
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[[Category: Liu, D]]
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[[Category: Neil, K]]
[[Category: Sanishvili, R]]
[[Category: Sanishvili, R]]
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[[Category: Neil, K]]
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[[Category: Silverman, R B]]
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[[Category: Liu, D]]
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[[Category: Wu, R]]
[[Category: Wu, R]]
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[[Category: Dustin, D.H]]
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[[Category: Biological evaluation]]
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[[Category: Emma, D]]
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[[Category: Mechanistic studies of con-formationally-restricted gaba-aminotransferase inactivator]]
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[[Category: Silverman, R.B]]
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[[Category: Synthesis]]
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[[Category: Lee, H.V]]
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[[Category: Transferase]]

Revision as of 02:48, 21 February 2016

GABA-aminotransferase inactivated by conformationally-restricted inactivator

4y0i, resolution 1.66Å

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