B-DNA tour
From Proteopedia
(Difference between revisions)
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==B-form DNA== | ==B-form DNA== | ||
<StructureSection load='1bna' size='400' side='right' caption='B-DNA' scene='72/725442/B-dna_overview/2'> | <StructureSection load='1bna' size='400' side='right' caption='B-DNA' scene='72/725442/B-dna_overview/2'> | ||
| + | Source <ref>PMID:7071593</ref> | ||
== Structural highlights == | == Structural highlights == | ||
<UL> | <UL> | ||
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DNA is usually found in the B form under physiological conditions. The B-form conformation is stabilized by water molecules bound to the minor groove. You can see them as red dots <scene name='72/725442/Water_spine/1'>in this view</scene>. Sometimes kinks are found in the B helix at transcriptional control regions. These kinks can either be intrinsic to the DNA sequence or caused by transcription factor binding. | DNA is usually found in the B form under physiological conditions. The B-form conformation is stabilized by water molecules bound to the minor groove. You can see them as red dots <scene name='72/725442/Water_spine/1'>in this view</scene>. Sometimes kinks are found in the B helix at transcriptional control regions. These kinks can either be intrinsic to the DNA sequence or caused by transcription factor binding. | ||
| - | You can compare it with the DNA forms by looking at this [http://proteopedia.org/wiki/images/d/d3/JnABZ3d.gif 3D red-blue | + | You can compare it with the DNA forms by looking at this [http://proteopedia.org/wiki/images/d/d3/JnABZ3d.gif 3D red-blue stereo picture of A, B, and Z DNA] |
</StructureSection> | </StructureSection> | ||
==See Also== | ==See Also== | ||
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* An interactive tutorial on [http://dna.molviz.org DNA Structure], ''disponible también en español'' and eight other languages. | * An interactive tutorial on [http://dna.molviz.org DNA Structure], ''disponible también en español'' and eight other languages. | ||
== References == | == References == | ||
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JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
<references /> | <references /> | ||
Revision as of 13:42, 22 February 2016
B-form DNA
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See Also
- Z-DNA model tour and Z-DNA
- A-RNA tour
- A more general overview will be found at DNA.
- Forms of DNA shows a side-by-side comparison of A, B, and Z forms of DNA.
- An interactive tutorial on DNA Structure, disponible también en español and eight other languages.
References
JSmol in Proteopedia [2] or to the article describing Jmol [3] to the rescue.
- ↑ Dickerson RE, Drew HR, Conner BN, Wing RM, Fratini AV, Kopka ML. The anatomy of A-, B-, and Z-DNA. Science. 1982 Apr 30;216(4545):475-85. PMID:7071593
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
