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==Introduction== | ==Introduction== | ||
<Structure load='2jch' size='300' frame='true' align='right' caption='2jch, Saves cells from dying since the appearance of life ' /> | <Structure load='2jch' size='300' frame='true' align='right' caption='2jch, Saves cells from dying since the appearance of life ' /> | ||
| - | Penicillin-binding protein has four ligands, one of which is <scene name='48/483886/Edo_ligand/1'>the electron-deficient olefin ligand or EDO</scene> | + | Outline: |
| + | 1) Why is it important? Penicillin-binding proteins are essential for cell wall biogenesis. General info about bacterial cell wall biogenesis. Also, how bacteria mutate in order to avoid binding to beta-lactam. | ||
| + | 2) Ligands, in particular <scene name='48/483886/Lactivicin/1'>phenoxyacetyl lactivicin</scene>. Also, how PBP binds lactivicin. | ||
| + | Sample green scene: Penicillin-binding protein has four ligands, one of which is <scene name='48/483886/Edo_ligand/1'>the electron-deficient olefin ligand or EDO</scene> | ||
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Revision as of 23:53, 22 February 2016
| This Sandbox is Reserved from January 19, 2016, through August 31, 2016 for use for Proteopedia Team Projects by the class Chemistry 423 Biochemistry for Chemists taught by Lynmarie K Thompson at University of Massachusetts Amherst, USA. This reservation includes Sandbox Reserved 425 through Sandbox Reserved 439. |
Contents |
Penicillin binding protein/lactivicin (inhibitor) (2jch)
by Tyler Carpenter, Samuel Pierce, Hyunjoon Choi, Anton El Khoury and Tiankai Zhang
Student Projects for UMass Chemistry 423 Spring 2016
Introduction
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Outline:
1) Why is it important? Penicillin-binding proteins are essential for cell wall biogenesis. General info about bacterial cell wall biogenesis. Also, how bacteria mutate in order to avoid binding to beta-lactam.
2) Ligands, in particular . Also, how PBP binds lactivicin.
Sample green scene: Penicillin-binding protein has four ligands, one of which is
Overall Structure
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Binding Interactions
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Additional Features
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Quiz Question 1
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See Also
Credits
Introduction - name of team member
Overall Structure - name of team member
Drug Binding Site - name of team member
Additional Features - name of team member
Quiz Question 1 - name of team member
