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Revision as of 16:08, 25 February 2016 (edit) Lynmarie K Thompson (Talk | contribs) (→'''P2Y12 Receptor in Complex with Clopidogrel (4ntj)''') ← Previous diff		Revision as of 07:12, 26 February 2016 (edit) (undo) Student (Talk | contribs) (→Credits) Next diff →
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	==Credits==		==Credits==
-	Introduction - name of team member	+	Introduction - Adam Murphy
-	Overall Structure - name of team member	+	Overall Structure - Cora Ricker
	Drug Binding Site - name of team member		Drug Binding Site - name of team member

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Revision as of 07:12, 26 February 2016

This Sandbox is Reserved from January 19, 2016, through August 31, 2016 for use for Proteopedia Team Projects by the class Chemistry 423 Biochemistry for Chemists taught by Lynmarie K Thompson at University of Massachusetts Amherst, USA. This reservation includes Sandbox Reserved 425 through Sandbox Reserved 439.

Contents 1 P2Y12 Receptor in Complex with Clopidogrel (4ntj)[1] 2 Introduction 3 Overall Structure 4 Binding Interactions 5 Additional Features 6 Quiz Question 1 7 See Also 8 Credits 9 References

P2Y12 Receptor in Complex with Clopidogrel (4ntj)^[1]

by [Cora Ricker, Lauren Timmins, Aidan Finnerty, Adam Murphy, Duy Nguyen]

Student Projects for UMass Chemistry 423 Spring 2016

Introduction

spinqualitylabelsall models 4ntj, Insert caption here Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

.

Overall Structure

spinqualitylabelsall models 4ntj, Overall Structure Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

The is mostly made up of alpha helices, shown in pink. The beta strands are shown in yellow. Polar vs nonpolar:Polar regions are pink. Nonpolar, or hyrophobic, regions are grey.

Binding Interactions

spinqualitylabelsall models pdbcode, Insert caption here Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Additional Features

spinqualitylabelsall models pdbcode, Insert caption here Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Quiz Question 1

spinqualitylabelsall models pdbcode, Insert caption here Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

See Also

• 4ntj
• 4pxz
• 4py0
• 1vz1

Credits

Introduction - Adam Murphy

Overall Structure - Cora Ricker

Drug Binding Site - name of team member

Additional Features - name of team member

Quiz Question 1 - name of team member

References

1. ↑ Zhang K, Zhang J, Gao ZG, Zhang D, Zhu L, Han GW, Moss SM, Paoletta S, Kiselev E, Lu W, Fenalti G, Zhang W, Muller CE, Yang H, Jiang H, Cherezov V, Katritch V, Jacobson KA, Stevens RC, Wu B, Zhao Q. Structure of the human P2Y12 receptor in complex with an antithrombotic drug. Nature. 2014 May 1;509(7498):115-8. doi: 10.1038/nature13083. Epub 2014 Mar 23. PMID:24670650 doi:http://dx.doi.org/10.1038/nature13083