5f3z
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Dengue serotype 3 RNA-dependent RNA polymerase bound to PC-79-SH52== | |
| - | + | <StructureSection load='5f3z' size='340' side='right' caption='[[5f3z]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5f3z]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F3Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5F3Z FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5V5:2-(4-METHOXY-3-THIOPHEN-2-YL-PHENYL)ETHANOIC+ACID'>5V5</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5f3t|5f3t]], [[5f41|5f41]]</td></tr> |
| - | [[Category: Noble, C | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5f3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f3z OCA], [http://pdbe.org/5f3z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5f3z RCSB], [http://www.ebi.ac.uk/pdbsum/5f3z PDBsum]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q6DLV0_9FLAV Q6DLV0_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS000336_004_099774] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Noble, C G]] | ||
| + | [[Category: Dengue]] | ||
| + | [[Category: Rdrp inhibitor]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 18:20, 26 February 2016
Dengue serotype 3 RNA-dependent RNA polymerase bound to PC-79-SH52
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