Sandbox Wabash 24 Fumarase

(Difference between revisions)

Revision as of 18:37, 27 February 2016

↑ Weaver T, Lees M, Banaszak L. Mutations of fumarase that distinguish between the active site and a nearby dicarboxylic acid binding site. Protein Sci. 1997 Apr;6(4):834-42. PMID:9098893

@@ Line 1: / Line 1: @@
 == Structure of Fumarase Active Site==
 <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''>
-This is a default text for your page '''Sandbox Wabash 24 Fumarase'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
+When studying fumarase 2 sites were identified to potentially be the active site. The first site (A-site)binds inhibitors (citrate, and pyromellitic acid) and is made up of parts of 3 of the 4 subunits that comprise fumarase. The second site (B-site) binds L-malate and is made up by parts of 1 of the 4 subunits. <ref>PMID:9098893</ref>.
-You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
 == Function ==