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Sandbox Wabash 10 Fumarase
From Proteopedia
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| - | =='''The Debated Fumarase Active Site'''== | + | Fumarase C is an enzyme from E. coli (EFumC) that catalyzes the hydration/dehydration reaction between L-malate and fumarate. It catalyzes the hydration of the double bond to form malate. The hydration reaction continues through a carbanion transition state. It is a non-iron containing enzyme and has a high degree of homology with eukaryotic enzymes. Its homology with cytosolic and mitochondrial enzymes in eukaryotic cells makes it ideal for research. Through x-ray crystallography it has been shown that the enzyme is comprised of a unusual subunit arrangement composed of a core of 20 α-helices, 5 in each of the subunits. |
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| + | =='''The Debated Fumarase C Active Site'''== | ||
Revision as of 23:58, 28 February 2016
Fumarase
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References
[2].
