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- | ==Crystal Structure of the Manihot esculenta Hydroxynitrile Lyase (MeHNL) 3KP triple mutant==
| + | #REDIRECT [[3x3h]] This PDB entry is obsolete and replaced by 3x3h |
- | <StructureSection load='3rkt' size='340' side='right' caption='[[3rkt]], [[Resolution|resolution]] 2.91Å' scene=''>
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- | == Structural highlights ==
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- | <table><tr><td colspan='2'>[[3rkt]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Manihot_esculenta Manihot esculenta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RKT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RKT FirstGlance]. <br>
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- | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rks|3rks]]</td></tr>
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- | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3983 Manihot esculenta])</td></tr>
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- | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxynitrilase Hydroxynitrilase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.37 4.1.2.37] </span></td></tr>
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- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rkt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rkt RCSB], [http://www.ebi.ac.uk/pdbsum/3rkt PDBsum]</span></td></tr>
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- | </table>
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- | == Function ==
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- | [[http://www.uniprot.org/uniprot/HNL_MANES HNL_MANES]] Involved in cyanogenesis, the release of HCN from injured tissues. Decomposes a varieties of (R) or (S) cyanohydrins into HCN and the corresponding aldehydes and ketones. The natural substrate of this enzyme is (S)-acetone cyanohydrin.
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- | __TOC__
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- | </StructureSection>
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- | [[Category: Hydroxynitrilase]]
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- | [[Category: Manihot esculenta]]
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- | [[Category: Asano, Y]]
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- | [[Category: Cielo, C B.C]]
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- | [[Category: Dadashipour, M]]
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- | [[Category: Komeda, H]]
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- | [[Category: Mizushima, T]]
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- | [[Category: Suzuki, A]]
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- | [[Category: Yamane, T]]
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- | [[Category: Acetate cyanohydrin]]
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- | [[Category: Cyanohydrin]]
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- | [[Category: Lyase]]
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- | [[Category: Reversible]]
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- | [[Category: Stereospecific metabolism]]
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