3x3h

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'''Unreleased structure'''
 
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The entry 3x3h is ON HOLD until Paper Publication
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==Crystal Structure of the Manihot esculenta Hydroxynitrile Lyase (MeHNL) 3KP (K176P, K199P, K224P) triple mutant==
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<StructureSection load='3x3h' size='340' side='right' caption='[[3x3h]], [[Resolution|resolution]] 2.88&Aring;' scene=''>
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Authors: Cielo, C.B.C., Yamane, T., Asano, Y., Dadashipour, M., Suzuki, A., Mizushima, T., Komeda, H., Okazaki, S.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3x3h]] is a 8 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3rkt 3rkt]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3X3H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3X3H FirstGlance]. <br>
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Description: Crystal Structure of the Manihot esculenta Hydroxynitrile Lyase (MeHNL) 3KP (K176P, K199P, K224P) triple mutant
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(S)-hydroxynitrile_lyase (S)-hydroxynitrile lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.47 4.1.2.47] </span></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3x3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3x3h OCA], [http://pdbe.org/3x3h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3x3h RCSB], [http://www.ebi.ac.uk/pdbsum/3x3h PDBsum]</span></td></tr>
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[[Category: Okazaki, S]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/HNL_MANES HNL_MANES]] Involved in cyanogenesis, the release of HCN from injured tissues. Decomposes a varieties of (R) or (S) cyanohydrins into HCN and the corresponding aldehydes and ketones. The natural substrate of this enzyme is (S)-acetone cyanohydrin.
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__TOC__
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</StructureSection>
[[Category: Asano, Y]]
[[Category: Asano, Y]]
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[[Category: Cielo, C B.C]]
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[[Category: Dadashipour, M]]
[[Category: Komeda, H]]
[[Category: Komeda, H]]
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[[Category: Dadashipour, M]]
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[[Category: Mizushima, T]]
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[[Category: Okazaki, S]]
[[Category: Suzuki, A]]
[[Category: Suzuki, A]]
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[[Category: Mizushima, T]]
 
[[Category: Yamane, T]]
[[Category: Yamane, T]]
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[[Category: Cielo, C.B.C]]
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[[Category: Hydroxynitrilase]]
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[[Category: Lyase]]

Revision as of 14:56, 2 March 2016

Crystal Structure of the Manihot esculenta Hydroxynitrile Lyase (MeHNL) 3KP (K176P, K199P, K224P) triple mutant

3x3h, resolution 2.88Å

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