This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5e9o
From Proteopedia
(Difference between revisions)
m (Protected "5e9o" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Spirochaeta thermophila X module - CBM64 - mutant G504A== | |
| + | <StructureSection load='5e9o' size='340' side='right' caption='[[5e9o]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5e9o]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E9O FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=I3C:5-AMINO-2,4,6-TRIIODOBENZENE-1,3-DICARBOXYLIC+ACID'>I3C</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e9o OCA], [http://pdbe.org/5e9o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e9o RCSB], [http://www.ebi.ac.uk/pdbsum/5e9o PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Spirochaeta thermophila secretes seven glycoside hydrolases for plant biomass degradation that carry a carbohydrate-binding module 64 (CBM64) appended at the C-terminus. CBM64 adsorbs to various beta1-4-linked pyranose substrates showing high affinity for cellulose. We present the first crystal structure of a CBM64 at 1.2 A resolution, which reveals a jelly-roll-like fold corresponding to a surface-binding type A CBM. Modeling of its interaction with cellulose indicates that CBM64 achieves association with the hydrophobic face of beta-linked pyranose chains via a unique coplanar arrangement of four exposed tryptophan side chains. This article is protected by copyright. All rights reserved. | ||
| - | + | Structural basis for cellulose binding by the type A carbohydrate-binding module 64 of Spirochaeta thermophila.,Schiefner A, Angelov A, Liebl W, Skerra A Proteins. 2016 Feb 12. doi: 10.1002/prot.25010. PMID:26868291<ref>PMID:26868291</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| + | <div class="pdbe-citations 5e9o" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Schiefner, A]] | [[Category: Schiefner, A]] | ||
[[Category: Skerra, A]] | [[Category: Skerra, A]] | ||
| + | [[Category: Carbohydrate-binding module 64]] | ||
| + | [[Category: Cbm64]] | ||
| + | [[Category: Cellulose and xylan binding]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Jelly roll]] | ||
| + | [[Category: Type a cbm]] | ||
Revision as of 15:01, 2 March 2016
Spirochaeta thermophila X module - CBM64 - mutant G504A
| |||||||||||
