5e9o
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Spirochaeta thermophila X module - CBM64 - mutant G504A== | |
| + | <StructureSection load='5e9o' size='340' side='right' caption='[[5e9o]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5e9o]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E9O FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=I3C:5-AMINO-2,4,6-TRIIODOBENZENE-1,3-DICARBOXYLIC+ACID'>I3C</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e9o OCA], [http://pdbe.org/5e9o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e9o RCSB], [http://www.ebi.ac.uk/pdbsum/5e9o PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Spirochaeta thermophila secretes seven glycoside hydrolases for plant biomass degradation that carry a carbohydrate-binding module 64 (CBM64) appended at the C-terminus. CBM64 adsorbs to various beta1-4-linked pyranose substrates showing high affinity for cellulose. We present the first crystal structure of a CBM64 at 1.2 A resolution, which reveals a jelly-roll-like fold corresponding to a surface-binding type A CBM. Modeling of its interaction with cellulose indicates that CBM64 achieves association with the hydrophobic face of beta-linked pyranose chains via a unique coplanar arrangement of four exposed tryptophan side chains. This article is protected by copyright. All rights reserved. | ||
| - | + | Structural basis for cellulose binding by the type A carbohydrate-binding module 64 of Spirochaeta thermophila.,Schiefner A, Angelov A, Liebl W, Skerra A Proteins. 2016 Feb 12. doi: 10.1002/prot.25010. PMID:26868291<ref>PMID:26868291</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| + | <div class="pdbe-citations 5e9o" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Schiefner, A]] | [[Category: Schiefner, A]] | ||
[[Category: Skerra, A]] | [[Category: Skerra, A]] | ||
| + | [[Category: Carbohydrate-binding module 64]] | ||
| + | [[Category: Cbm64]] | ||
| + | [[Category: Cellulose and xylan binding]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Jelly roll]] | ||
| + | [[Category: Type a cbm]] | ||
Revision as of 15:01, 2 March 2016
Spirochaeta thermophila X module - CBM64 - mutant G504A
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