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5agt

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'''Unreleased structure'''
 
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The entry 5agt is ON HOLD until Paper Publication
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==Crystal structure of the LeuRS editing domain of Mycobacterium tuberculosis in complex with the adduct (S)-3-(Aminomethyl)-4-chloro-7-ethoxybenzo[c][1,2]oxaborol-1(3H)-ol-AMP==
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<StructureSection load='5agt' size='340' side='right' caption='[[5agt]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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Authors: Palencia, A., Li, X., Alley, M.R.K., Ding, C., Easom, E.E., Hernandez, V., Meewan, M., Mohan, M., Rock, F.L., Franzblau, S.G., Wang, Y., Lenaerts, A.J., Parish, T., Cooper, C.B., Waters, M.G., Ma, Z., Mendoza, A., Barros, D., Cusack, S., Plattner, J.J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5agt]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AGT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AGT FirstGlance]. <br>
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Description: Crystal structure of the LeuRS editing domain of Mycobacterium tuberculosis in complex with the adduct AN6426-AMP
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2H:4-CHLORO-3-AMINOMETHYL-7-[ETHOXY]-3H-BENZO[C][1,2]OXABOROL-1-OL+MODIFIED+ADENOSINE'>A2H</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5agr|5agr]], [[5ags|5ags]]</td></tr>
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[[Category: Mendoza, A]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Leucine--tRNA_ligase Leucine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.4 6.1.1.4] </span></td></tr>
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[[Category: Waters, M.G]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5agt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5agt OCA], [http://pdbe.org/5agt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5agt RCSB], [http://www.ebi.ac.uk/pdbsum/5agt PDBsum]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
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[[Category: Leucine--tRNA ligase]]
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[[Category: Alley, M R.K]]
[[Category: Barros, D]]
[[Category: Barros, D]]
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[[Category: Rock, F.L]]
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[[Category: Cooper, C B]]
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[[Category: Franzblau, S.G]]
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[[Category: Alley, M.R.K]]
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[[Category: Cusack, S]]
[[Category: Cusack, S]]
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[[Category: Cooper, C.B]]
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[[Category: Ding, C]]
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[[Category: Wang, Y]]
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[[Category: Easom, E E]]
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[[Category: Franzblau, S G]]
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[[Category: Hernandez, V]]
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[[Category: Lenaerts, A J]]
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[[Category: Li, X]]
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[[Category: Ma, Z]]
[[Category: Meewan, M]]
[[Category: Meewan, M]]
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[[Category: Plattner, J.J]]
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[[Category: Mendoza, A]]
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[[Category: Li, X]]
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[[Category: Lenaerts, A.J]]
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[[Category: Ding, C]]
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[[Category: Mohan, M]]
[[Category: Mohan, M]]
[[Category: Palencia, A]]
[[Category: Palencia, A]]
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[[Category: Ma, Z]]
 
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[[Category: Hernandez, V]]
 
[[Category: Parish, T]]
[[Category: Parish, T]]
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[[Category: Easom, E.E]]
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[[Category: Plattner, J J]]
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[[Category: Rock, F L]]
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[[Category: Wang, Y]]
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[[Category: Waters, M G]]
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[[Category: Aminoacyl-trna synthetase]]
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[[Category: Leucine-trna ligase activity]]
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[[Category: Ligase]]
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[[Category: Novel boron inhibitors of leur]]
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[[Category: Protein biosynthesis]]

Revision as of 15:20, 2 March 2016

Crystal structure of the LeuRS editing domain of Mycobacterium tuberculosis in complex with the adduct (S)-3-(Aminomethyl)-4-chloro-7-ethoxybenzo[c][1,2]oxaborol-1(3H)-ol-AMP

5agt, resolution 1.45Å

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