Tdp-43
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | <Structure load='http://proteopedia.org/wiki/index.php/Image:2n2c_ligalza0.pdb' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | + | <Structure load='http://proteopedia.org/wiki/index.php/Image:2n2c_ligalza0.pdb' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' />TDP-43 helical stabilizers |
<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> | ||
This is the healthy helical coil (residues 307-349) of TDP-43. A key biomolecular cause of ALS appears to be a helix-sheet transition in this area, leading to the formation of protein fibrils.<Structure load='2n2c_ligalza0.pdb' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> '''Tdp-43'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | This is the healthy helical coil (residues 307-349) of TDP-43. A key biomolecular cause of ALS appears to be a helix-sheet transition in this area, leading to the formation of protein fibrils.<Structure load='2n2c_ligalza0.pdb' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> '''Tdp-43'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
Revision as of 14:28, 3 March 2016
|
| |||||||||||
References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
