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5i3r
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor== | |
| - | + | <StructureSection load='5i3r' size='340' side='right' caption='[[5i3r]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5i3r]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I3R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5I3R FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IDK:N-[6-(3-{[(CYCLOPROPYLMETHYL)SULFONYL]AMINO}PHENYL)-1H-INDAZOL-3-YL]CYCLOPROPANECARBOXAMIDE'>IDK</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5i3o|5i3o]], [[4w9w|4w9w]], [[4w9x|4w9x]]</td></tr> |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5i3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i3r OCA], [http://pdbe.org/5i3r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5i3r RCSB], [http://www.ebi.ac.uk/pdbsum/5i3r PDBsum]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BMP2K_HUMAN BMP2K_HUMAN]] May be involved in osteoblast differentiation. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Non-specific serine/threonine protein kinase]] | ||
| + | [[Category: Arrowsmith, C H]] | ||
| + | [[Category: Arruda, P]] | ||
| + | [[Category: Axtman, A]] | ||
[[Category: Bountra, C]] | [[Category: Bountra, C]] | ||
| - | [[Category: | + | [[Category: Counago, R M]] |
| - | [[Category: | + | [[Category: Drewry, D]] |
| - | [[Category: Edwards, A | + | [[Category: Edwards, A M]] |
| - | [[Category: | + | [[Category: Elkins, J M]] |
[[Category: Gileadi, O]] | [[Category: Gileadi, O]] | ||
| - | [[Category: | + | [[Category: Krojer, T]] |
| - | [[Category: Structural | + | [[Category: Structural genomic]] |
| + | [[Category: Savitsky, P]] | ||
| + | [[Category: Sorrell, F J]] | ||
| + | [[Category: Wells, C]] | ||
| + | [[Category: Willson, T M]] | ||
| + | [[Category: Zhang, C]] | ||
| + | [[Category: Zuercher, W]] | ||
| + | [[Category: Protein kinase domain]] | ||
| + | [[Category: Sgc]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 04:00, 10 March 2016
Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor
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Categories: Non-specific serine/threonine protein kinase | Arrowsmith, C H | Arruda, P | Axtman, A | Bountra, C | Counago, R M | Drewry, D | Edwards, A M | Elkins, J M | Gileadi, O | Krojer, T | Structural genomic | Savitsky, P | Sorrell, F J | Wells, C | Willson, T M | Zhang, C | Zuercher, W | Protein kinase domain | Sgc | Transferase | Transferase-transferase inhibitor complex
