User:Allie Paton/Sandbox 1181
From Proteopedia
< User:Allie Paton(Difference between revisions)
| Line 7: | Line 7: | ||
<scene name='72/727084/Temp_map/1'>Temp Map</scene> | <scene name='72/727084/Temp_map/1'>Temp Map</scene> | ||
| - | == Function == | + | == Function of Glucagon Receptor == |
| + | |||
== Disease == | == Disease == | ||
=== Diabetes Mellitus === | === Diabetes Mellitus === | ||
| + | === Biological Function of Glucagon === | ||
== Biochemical Significance == | == Biochemical Significance == | ||
| Line 16: | Line 18: | ||
=== Ligand Binding === | === Ligand Binding === | ||
=== Sequence Conservation and Homology === | === Sequence Conservation and Homology === | ||
| + | === Conformational Change === | ||
== Structural highlights == | == Structural highlights == | ||
=== Crucial Structural Interactions === | === Crucial Structural Interactions === | ||
| + | === Peptide Sequence === | ||
| + | === Active Binding Sites === | ||
| + | |||
== Relevance == | == Relevance == | ||
=== Class B in Comparison to Class A === | === Class B in Comparison to Class A === | ||
[[Image:Class B.png |100 px|left|thumb|Figure Legend]] | [[Image:Class B.png |100 px|left|thumb|Figure Legend]] | ||
| + | ==== Structural Similarities ==== | ||
| + | ==== Sequential Similarities ==== | ||
| + | === Current Drug Targets === | ||
== Future Direction == | == Future Direction == | ||
=== Drug Development === | === Drug Development === | ||
| + | === Possible Structures for Agonists === | ||
Current revision
Structure of Class B Human Glucagon G-Protein Coupled Receptors
| |||||||||||
References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
