Gyrase

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GyrA inhibitor [[Ciprofloxacin]] is used as antibiotic drug.
GyrA inhibitor [[Ciprofloxacin]] is used as antibiotic drug.
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==3D Structure of Gyrase==
==3D Structure of Gyrase==

Revision as of 07:49, 20 March 2016

Gyrase subunit A N-terminal (yellow) and subunit B C-terminal (green) complex with DNA (magenta, cyan), inhibitor, sulfate and Mn+2 ion (purple) (PDB entry 4plb)

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3D Structure of Gyrase

Updated on 20-March-2016

Additional Resources

For additional information, see: Bacterial Infections

References

  1. ↑ Reece RJ, Maxwell A. DNA gyrase: structure and function. Crit Rev Biochem Mol Biol. 1991;26(3-4):335-75. PMID:1657531 doi:http://dx.doi.org/10.3109/10409239109114072
  2. ↑ Napoli A, Valenti A, Salerno V, Nadal M, Garnier F, Rossi M, Ciaramella M. Functional interaction of reverse gyrase with single-strand binding protein of the archaeon Sulfolobus. Nucleic Acids Res. 2005 Jan 26;33(2):564-76. Print 2005. PMID:15673717 doi:http://dx.doi.org/10.1093/nar/gki202

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Michal Harel, Alexander Berchansky, David Canner, Joel L. Sussman

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