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Sandbox Reserved 1174
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== Function == | == Function == | ||
| - | Human lysophosphatidic acid receptor 1 is coupled to a heterotrimeric G protein. The three G alpha proteins that LPA1 couples to are Gi, Gq, and G12/13. | + | Human lysophosphatidic acid receptor 1 is coupled to a heterotrimeric G protein. The three G alpha proteins that LPA1 couples to are Gi, Gq, and G12/13. The main function of the Gi alpha subunit is the inhibition of the production of cAMP from ATP. cAMP... The Gq alpha subunit activates phospholipase C. The G12/13 subunit regulates cell processes through the use of guanine nucleotide exchange factors. |
Revision as of 12:18, 22 March 2016
| This Sandbox is Reserved from Jan 11 through August 12, 2016 for use in the course CH462 Central Metabolism taught by R. Jeremy Johnson at the Butler University, Indianapolis, USA. This reservation includes Sandbox Reserved 1160 through Sandbox Reserved 1184. |
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Human Lysophosphatidic Acid Receptor 1
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
