1h1k
From Proteopedia
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|PDB= 1h1k |SIZE=350|CAPTION= <scene name='initialview01'>1h1k</scene>, resolution 10.Å | |PDB= 1h1k |SIZE=350|CAPTION= <scene name='initialview01'>1h1k</scene>, resolution 10.Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= | + | |LIGAND= <scene name='pdbligand=A:ADENOSINE-5'-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=U:URIDINE-5'-MONOPHOSPHATE'>U</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h1k OCA], [http://www.ebi.ac.uk/pdbsum/1h1k PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1h1k RCSB]</span> | ||
}} | }} | ||
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[[Category: Stuart, D I.]] | [[Category: Stuart, D I.]] | ||
[[Category: Sutton, G.]] | [[Category: Sutton, G.]] | ||
| - | [[Category: | + | [[Category: virus,viral protein,rna]] |
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:55:43 2008'' |
Revision as of 17:55, 30 March 2008
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| , resolution 10.Å | |||||||
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| Ligands: | , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
Overview
Double-stranded RNA (dsRNA) viruses conceal their genome from the host to avoid triggering unfavorable cellular responses. The crystal structure of the core of one such virus, bluetongue virus, reveals an outer surface festooned with dsRNA. This may represent a deliberate strategy to sequester dsRNA released from damaged particles to prevent host cell shutoff.
About this Structure
1H1K is a Single protein structure of sequence from Bluetongue virus. Full crystallographic information is available from OCA.
Reference
The core of bluetongue virus binds double-stranded RNA., Diprose JM, Grimes JM, Sutton GC, Burroughs JN, Meyer A, Maan S, Mertens PP, Stuart DI, J Virol. 2002 Sep;76(18):9533-6. PMID:12186935
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