Sandbox Surcrase isomaltase

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Function

Sucrase isomaltase is a partially embedded integral protein located in the brush border of the small intestine. SI is responsible for catalyzing the hydrolysis of dietary carbohydrates that includes starch, sucrose, and isomaltase. It is composed of two subunits: sucrase and isomaltase. The gene that codes for SI is located on chromosome 3 and is composed of 48 exons. The brush border is an important function of absorption of minerals and amino acids the body can use. The border is composed of millions of microvilli tightly packed together that are anywhere from 100 to 2,000 nanometers. Some other key enzymes in the small intestine are glucoamylase (Maltase), lactase, and peptidases.

Disease

Relevance

Structural highlights

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