Sandbox WWC2
From Proteopedia
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==Introduction== | ==Introduction== | ||
| - | '' | + | ''Monoamine oxidase A (MAO-A) is an enzyme, encoded in the MAOA gene on the X chromosome, that is expressed on the outer surface of the mitochondrial membrane. Two isoforms of this enzyme are expressed on the membrane, MAO-A and MAO-B, and both are responsible for the oxidation of various amine-containing neurotransmitters and dietary amines. More specifically, MAO-A oxidizes serotonin, epinephrine, and norepinephrine; while MAO-B oxidizes phenylethylamine and benzylamine. Both isoforms of monoamine oxidase oxidize dopamine, tyramine, and N,N-dimethyltryptamine. '' |
<Structure load='2Z5X' size='500' frame='top' align='right' caption='Crystal Structure of Human Monoamine Oxidase A with Harmine' scene='Insert optional scene name here' /> | <Structure load='2Z5X' size='500' frame='top' align='right' caption='Crystal Structure of Human Monoamine Oxidase A with Harmine' scene='Insert optional scene name here' /> | ||
Revision as of 02:19, 13 April 2016
Contents |
Introduction
Monoamine oxidase A (MAO-A) is an enzyme, encoded in the MAOA gene on the X chromosome, that is expressed on the outer surface of the mitochondrial membrane. Two isoforms of this enzyme are expressed on the membrane, MAO-A and MAO-B, and both are responsible for the oxidation of various amine-containing neurotransmitters and dietary amines. More specifically, MAO-A oxidizes serotonin, epinephrine, and norepinephrine; while MAO-B oxidizes phenylethylamine and benzylamine. Both isoforms of monoamine oxidase oxidize dopamine, tyramine, and N,N-dimethyltryptamine.
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The , illustrated in the protein image to the right, in conjunction with the color key, below, indicates the directionality of the polypeptide chain.
| Amino Terminus | Carboxy Terminus |
Function
Disease
Relevance
Structural highlights
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
</StructureSection>
