Kdo-8-phosphate synthase
From Proteopedia
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| - | <StructureSection load='3fyp' size='450' side='right' scene='' caption='Metallo Kdo-8-phosphate synthase tetramer complex with phosphoenolpyruvate, glycerol, Cl- (green), Na+ (large purple) and Mn+2 (small purple) ion, [[3fyp]]'> | + | <StructureSection load='3fyp' size='450' side='right' scene='52/525184/Cv/2' caption='Metallo Kdo-8-phosphate synthase tetramer complex with phosphoenolpyruvate, glycerol, Cl- (green), Na+ (large purple) and Mn+2 (small purple) ion, [[3fyp]]'> |
== Function == | == Function == | ||
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== Structural highlights == | == Structural highlights == | ||
| - | The active site of the metallo KPS contains a divalent cation and the PEP substrate<ref>PMID:19447118</ref>. | + | The biological assembly of Metallo Kdo-8-phosphate synthase from ''Neisseria meningitidis'' is <scene name='52/525184/Cv/3'>homotetramer</scene>. The active site of the metallo KPS contains a divalent cation and the PEP substrate<ref>PMID:19447118</ref>. |
</StructureSection> | </StructureSection> | ||
==3D structures of Kdo-8-phosphate synthase== | ==3D structures of Kdo-8-phosphate synthase== | ||
Revision as of 14:33, 13 April 2016
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3D structures of Kdo-8-phosphate synthase
Updated on 13-April-2016
References
- ↑ Krosky DJ, Alm R, Berg M, Carmel G, Tummino PJ, Xu B, Yang W. Helicobacter pylori 3-deoxy-D-manno-octulosonate-8-phosphate (KDO-8-P) synthase is a zinc-metalloenzyme. Biochim Biophys Acta. 2002 Feb 11;1594(2):297-306. PMID:11904225
- ↑ Cochrane FC, Cookson TV, Jameson GB, Parker EJ. Reversing evolution: re-establishing obligate metal ion dependence in a metal-independent KDO8P synthase. J Mol Biol. 2009 Jul 24;390(4):646-61. Epub 2009 May 15. PMID:19447118 doi:10.1016/j.jmb.2009.05.014
