M2 protein
From Proteopedia
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| - | + | <StructureSection load='4c3e' size='350' side='right' caption='Human respiratory syncytial virus M2 protein (PDB entry [[4c3e]])' scene=''> | |
| - | <StructureSection load='4c3e' size='350' side='right' caption='Human | + | |
__TOC__ | __TOC__ | ||
== Function == | == Function == | ||
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The '''M2 protein''' (M2) is a proton selective ion channel of the influenza virus<ref>PMID:18045172</ref>. It is activated by low pH. M2 has 3 domains: an ectodomain, transmembrane domain (TM) and a C terminal cytoplasmic domain. See more in:<br /> | The '''M2 protein''' (M2) is a proton selective ion channel of the influenza virus<ref>PMID:18045172</ref>. It is activated by low pH. M2 has 3 domains: an ectodomain, transmembrane domain (TM) and a C terminal cytoplasmic domain. See more in:<br /> | ||
[[M2 Proton Channel]]<br /> | [[M2 Proton Channel]]<br /> | ||
[[Molecular Playground/Influenza A M2 transmembrane domain]]<br /> | [[Molecular Playground/Influenza A M2 transmembrane domain]]<br /> | ||
[[M2 Proton Channel Inhibitor Pharmacokinetics]]. | [[M2 Proton Channel Inhibitor Pharmacokinetics]]. | ||
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| + | == Structural highlights == | ||
| + | M2 protein from Human respiratory syncytial virus contains 4 domains: Zn-binding, transmembrane (TM), core which binds RNA and a C terminal domain<ref>PMID:24434552</ref>. | ||
==3D structures of M2 protein== | ==3D structures of M2 protein== | ||
Revision as of 08:00, 14 April 2016
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