MEP cytidylyltransferase
From Proteopedia
(Difference between revisions)
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| - | <StructureSection load='1i52' size=' | + | <StructureSection load='1i52' size='450' side='right' caption='Structure of E. coli MEP cytidylyltransferase complex with CTP, Mg+2 (small light green) and Ca+2 (large green) (PDB code [[1i52]]). ' scene='59/595219/Cv/1'> |
== Function == | == Function == | ||
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== Structural highlights == | == Structural highlights == | ||
| - | The <scene name='59/595219/Cv/5'>active site of MEPCT contains an Mg+2 ion</scene><ref>PMID:11427897</ref>. Water molecules shown as red spheres. <scene name='59/595219/Cv/6'>Whole active site</scene>. | + | The biological assembly of ''E. coli'' MEPCT is <scene name='59/595219/Cv/7'>homodimer</scene>. The <scene name='59/595219/Cv/5'>active site of MEPCT contains an Mg+2 ion</scene><ref>PMID:11427897</ref>. Water molecules shown as red spheres. <scene name='59/595219/Cv/6'>Whole active site</scene>. |
</StructureSection> | </StructureSection> | ||
Revision as of 12:48, 20 April 2016
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3D structures of MEP cytidylyltransferase
Updated on 20-April-2016
References
- ↑ Friedrich R, Fuentes-Prior P, Ong E, Coombs G, Hunter M, Oehler R, Pierson D, Gonzalez R, Huber R, Bode W, Madison EL. Catalytic domain structures of MT-SP1/matriptase, a matrix-degrading transmembrane serine proteinase. J Biol Chem. 2002 Jan 18;277(3):2160-8. Epub 2001 Nov 5. PMID:11696548 doi:10.1074/jbc.M109830200
- ↑ Tsang A, Seidle H, Jawaid S, Zhou W, Smith C, Couch RD. Francisella tularensis 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase: kinetic characterization and phosphoregulation. PLoS One. 2011;6(6):e20884. doi: 10.1371/journal.pone.0020884. Epub 2011 Jun 9. PMID:21694781 doi:http://dx.doi.org/10.1371/journal.pone.0020884
- ↑ Richard SB, Bowman ME, Kwiatkowski W, Kang I, Chow C, Lillo AM, Cane DE, Noel JP. Structure of 4-diphosphocytidyl-2-C- methylerythritol synthetase involved in mevalonate- independent isoprenoid biosynthesis. Nat Struct Biol. 2001 Jul;8(7):641-8. PMID:11427897 doi:10.1038/89691
