Metabotropic glutamate receptor

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[[Metabotropic glutamate receptor|Metabotropic glutamate receptors]] are [[Glutamate Receptors|glutamate receptors]] that activate ion channels indirectly through a signalling cascade involving G proteins. They are members of the large class of seven-transmembrane domain receptors, the [[G protein-coupled receptor|G protein-coupled receptors]]. See also [[Ligand Binding N-Terminal of Metabotropic Glutamate Receptors]].
 
<Structure load='1isr' size='500' side='right' caption='Structure of the binding domain of the Metabotropic Glutamate Receptor, GluR1, bound to glutamate and gadolinium ions ([[1isr]])' scene=' '/>
<Structure load='1isr' size='500' side='right' caption='Structure of the binding domain of the Metabotropic Glutamate Receptor, GluR1, bound to glutamate and gadolinium ions ([[1isr]])' scene=' '/>
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[[Metabotropic glutamate receptor|Metabotropic glutamate receptors]] are [[Glutamate Receptors|glutamate receptors]] that activate ion channels indirectly through a signaling cascade involving G proteins<ref>PMID:20716669</ref>. They are members of the large class of seven-transmembrane domain receptors, the [[G protein-coupled receptor|G protein-coupled receptors]]. See also [[Ligand Binding N-Terminal of Metabotropic Glutamate Receptors]].
Articles in Proteopedia concerning Toll-like Receptors include:
Articles in Proteopedia concerning Toll-like Receptors include:
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[[Alzheimer's Disease]]<br/>
[[Alzheimer's Disease]]<br/>
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* [[Ligand Binding N-Terminal of Metabotropic Glutamate Receptors]]
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 08:37, 21 April 2016

Structure of the binding domain of the Metabotropic Glutamate Receptor, GluR1, bound to glutamate and gadolinium ions (1isr)

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Metabotropic glutamate receptors are glutamate receptors that activate ion channels indirectly through a signaling cascade involving G proteins[1]. They are members of the large class of seven-transmembrane domain receptors, the G protein-coupled receptors. See also Ligand Binding N-Terminal of Metabotropic Glutamate Receptors.

Articles in Proteopedia concerning Toll-like Receptors include:


3D structures of metabotropic glutamate receptor

Updated on 21-April-2016

See Also

Membrane Channels & Pumps
Ionotropic_Glutamate_Receptors
Alzheimer's Disease

References

  1. Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, Ogden KK, Hansen KB, Yuan H, Myers SJ, Dingledine R. Glutamate receptor ion channels: structure, regulation, and function. Pharmacol Rev. 2010 Sep;62(3):405-96. doi: 10.1124/pr.109.002451. PMID:20716669 doi:http://dx.doi.org/10.1124/pr.109.002451

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Michal Harel, Alexander Berchansky, Wayne Decatur, Nikki Hunter

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