Methane monooxygenase

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== Function ==
== Function ==
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'''Methane monooxygenase''' (MMO) catalyzes the oxidation of the C-H bond of methane and other alkanes. MMO catalyzes the conversion of CH4 and O2 to CH3OH and H2O using NADPH as reducing agent. The '''soluble MMO (sMMO)''' has Fe-O-Fe in its active site while the '''particulate MMO (pMMO)''' has Cu in it. MMO is composed of 3 subunits.<br />
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'''Methane monooxygenase''' (MMO) catalyzes the oxidation of the C-H bond of methane and other alkanes. MMO catalyzes the conversion of CH<sub>4</sub> and O2 to CH3OH and H2O using NADPH as reducing agent. The '''soluble MMO (sMMO)''' has Fe-O-Fe in its active site while the '''particulate MMO (pMMO)''' has Cu in it. MMO is composed of 3 subunits.<br />
* Subunit α is the hydroxylase and contains the di-iron active site.<br />
* Subunit α is the hydroxylase and contains the di-iron active site.<br />
* Subunit β is a reductase which contains the co-factors FAD and 2Fe-2S complex.<br />
* Subunit β is a reductase which contains the co-factors FAD and 2Fe-2S complex.<br />

Revision as of 09:49, 21 April 2016

Structure of methane monooxygenase α (grey and green) +β (pink and yellow) +γ (magenta and cyan) subunits complex with Fe+3 (red), Ca+2 (green) and dibromomethane (PDB code 1fz8).

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3D structures of methane monooxygenase

Updated on 21-April-2016

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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