1hxb

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|PDB= 1hxb |SIZE=350|CAPTION= <scene name='initialview01'>1hxb</scene>, resolution 2.30&Aring;
|PDB= 1hxb |SIZE=350|CAPTION= <scene name='initialview01'>1hxb</scene>, resolution 2.30&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=QNC:2-CARBONYLQUINOLINE'>QNC</scene> and <scene name='pdbligand=DIQ:2-METHYL-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID'>DIQ</scene>
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|LIGAND= <scene name='pdbligand=DIQ:2-METHYL-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC+ACID'>DIQ</scene>, <scene name='pdbligand=DSG:D-ASPARAGINE'>DSG</scene>, <scene name='pdbligand=HPH:PHENYLALANINDIOL'>HPH</scene>, <scene name='pdbligand=NTB:TERTIARY-BUTYLAMINE'>NTB</scene>, <scene name='pdbligand=QNC:2-CARBONYLQUINOLINE'>QNC</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16]
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span>
|GENE= POL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10239 Viruses])
|GENE= POL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10239 Viruses])
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|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hxb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hxb OCA], [http://www.ebi.ac.uk/pdbsum/1hxb PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1hxb RCSB]</span>
}}
}}
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[[Category: Graves, B J.]]
[[Category: Graves, B J.]]
[[Category: Hatada, M H.]]
[[Category: Hatada, M H.]]
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[[Category: DIQ]]
 
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[[Category: QNC]]
 
[[Category: complex (aspartyl protease/inhibitor)]]
[[Category: complex (aspartyl protease/inhibitor)]]
[[Category: rna-directed dna polymerase]]
[[Category: rna-directed dna polymerase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:42:43 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:11:36 2008''

Revision as of 18:11, 30 March 2008


PDB ID 1hxb

Drag the structure with the mouse to rotate
, resolution 2.30Å
Ligands: , , , ,
Gene: POL (Viruses)
Activity: HIV-1 retropepsin, with EC number 3.4.23.16
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



HIV-1 PROTEINASE COMPLEXED WITH RO 31-8959


About this Structure

1HXB is a Single protein structure of sequence from Viruses. The following page contains interesting information on the relation of 1HXB with [HIV-1 Protease]. Full crystallographic information is available from OCA.

Reference

Novel binding mode of highly potent HIV-proteinase inhibitors incorporating the (R)-hydroxyethylamine isostere., Krohn A, Redshaw S, Ritchie JC, Graves BJ, Hatada MH, J Med Chem. 1991 Nov;34(11):3340-2. PMID:1956054

Page seeded by OCA on Sun Mar 30 21:11:36 2008

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