1i0e

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|SITE=
|SITE=
|LIGAND=
|LIGAND=
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|ACTIVITY= [http://en.wikipedia.org/wiki/Creatine_kinase Creatine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.3.2 2.7.3.2]
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Creatine_kinase Creatine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.3.2 2.7.3.2] </span>
|GENE=
|GENE=
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|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1i0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i0e OCA], [http://www.ebi.ac.uk/pdbsum/1i0e PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1i0e RCSB]</span>
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[[Category: double helix]]
[[Category: double helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:43:59 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:12:51 2008''

Revision as of 18:12, 30 March 2008


PDB ID 1i0e

Drag the structure with the mouse to rotate
, resolution 3.50Å
Activity: Creatine kinase, with EC number 2.7.3.2
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF CREATINE KINASE FROM HUMAN MUSCLE


Overview

The crystal structure of human muscle creatine kinase has been determined by the molecular-replacement method and refined at 3.5A resolution. The structures of both the monomer and the dimer closely resemble those of the other known structures in the creatine kinase family. Two types of dimers, one with a non-crystallographic twofold symmetry axis and the other with a crystallographic twofold symmetry axis, were found to exist simultaneously in the crystal. These dimers form an infinite "double-helix"-like structure along an unusual long crystallographic 3(1) axis.

About this Structure

1I0E is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Structure of human muscle creatine kinase., Shen YQ, Tang L, Zhou HM, Lin ZJ, Acta Crystallogr D Biol Crystallogr. 2001 Aug;57(Pt 8):1196-200. PMID:11517911

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